[Moxibustion on plaque psoriasis of blood stasis: a randomized controlled trial]

Zhongguo Zhen Jiu. 2021 Jul 12;41(7):762-6. doi: 10.13703/j.0255-2930.20200907-0004.
[Article in Chinese]

Abstract

Objective: To observe the short-term and long-term effects of moxibustion on plaque psoriasis of blood stasis, and to compare the curative effect between moxibustion and calcipotriol ointment.

Methods: A total of 80 patients with plaque psoriasis of blood stasis were randomly divided into an observation group (40 cases, 2 cases dropped off) and a control group (40 cases, 4 cases dropped off). Both groups were given routine medical vaseline topical emollient basic treatment. In the observation group, moxibustion was applied to ashi point (target skin lesions), Zusanli (ST 36), Xuehai (SP 10) and Qihai (CV 6) for 30 min each time, 3 times a week. The control group was treated with calcipotriol ointment (0.25 g each time, once in the morning and evening) on the target skin lesions. Both groups were treated for 8 weeks. The psoriasis area and severity index (PASI) score before and after treatment, main clinical symptoms of TCM score and dermatology life quality index (DLQI) score before and after treatment and 3 and 6 moths follow-up were observed in the two groups; the clinical efficacy after treatment was evaluated and the recurrence rates of the two groups were followed up for 3 and 6 months after treatment.

Results: After treatment, the PASI scores in the both groups were lower than before treatment (P<0.01). After treatment and 3 and 6 months follow-up, the main clinical symptoms of TCM scores and DLQI scores of the two groups were lower than those before treatment (P<0.05), and at 3 and 6 months follow-up, those in the observation group were lower than the control group (P<0.01). There was no statistically significant difference between the observation group and the control group in overall effective rate and target skin lesion effective rate (P>0.05). At 3 and 6 months follow-up, the overall recurrence rate and target skin lesion recurrence rate in the observation group were lower than those in the control group (P<0.05).

Conclusion: Both moxibustion and calcipotriol ointment have good short-term effects on plaque psoriasis of blood stasis. Moxibustion has more advantages in reducing the recurrence rate of psoriasis, improving the main clinical symptoms of TCM and quality of life.

目的:观察艾灸治疗血瘀证斑块型银屑病的近期和远期疗效,比较艾灸与卡泊三醇软膏的疗效。方法:将 80例血瘀证斑块型银屑病患者随机分为观察组(40例,脱落2例)和对照组(40例,脱落4例)。两组均给予常规医用凡士林外用润肤基础治疗。观察组于阿是穴(靶皮损局部)、足三里、血海、气海穴艾灸,每次30 min,每周治疗3次。对照组于靶皮损局部外用卡泊三醇软膏治疗(每次0.25 g,早晚各1次)。两组均治疗8周。观察两组患者治疗前后银屑病皮损面积与严重程度指数(PASI)评分,治疗前后及治疗后3、6个月随访中医主要临床症状评分及皮肤病生活质量指数(DLQI)评分;评定两组患者临床疗效及随访3、6个月的复发率。结果:治疗后,两组患者整体和靶皮损PASI评分均较治疗前降低(P<0.01)。治疗后及随访3、6个月时,两组患者中医主要临床症状评分、DLQI评分均较治疗前降低(P<0.05);随访3、6个月时,观察组低于对照组(P<0.01)。观察组整体总有效率和靶皮损总有效率与对照组比较差异无统计学意义(P>0.05)。随访3个月和6个月时,观察组整体复发率和靶皮损复发率均低于对照组(P<0.05)。结论:艾灸和卡泊三醇软膏均对血瘀证斑块型银屑病有较好的近期疗效,艾灸在降低银屑病复发率、改善临床症状、提高患者生活质量方面更具优势。.

Keywords: calcipotriol ointment; moxibustion; plaque psoriasis, blood stasis; randomized controlled trial (RCT).

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Acupuncture Points
  • Humans
  • Moxibustion*
  • Psoriasis* / drug therapy
  • Quality of Life
  • Treatment Outcome