Hemostatic Disorders: Physiology, Diagnostics, and Management

Clin J Oncol Nurs. 2021 Aug 1;25(4):379-382. doi: 10.1188/21.CJON.379-382.


A defect in any step of hemostasis can lead to potentially catastrophic results. The purpose of this article is to review hemostatic physiology, laboratory studies, and management of platelet and coagulation disorders to familiarize the advanced practice RN (APRN) with this often overlooked but critical system. Learning the underlying mechanisms allows for better understanding of the various disease states that can occur in the hematology and oncology settings.

Keywords: advanced practice; coagulopathy; critical care; hematology; hemostasis.

Publication types

  • Review

MeSH terms

  • Blood Coagulation Disorders* / diagnosis
  • Blood Coagulation Disorders* / therapy
  • Hematology*
  • Hemostasis
  • Hemostatic Disorders* / diagnosis
  • Hemostatic Disorders* / therapy
  • Humans