Orbital Plasmablastic Lymphoma: A Rare Variant of Diffuse Large B-Cell Lymphoma Staged and Followed Up by 18F-FDG PET/CT

Clin Nucl Med. 2022 Jan 1;47(1):e37-e38. doi: 10.1097/RLU.0000000000003805.


Plasmablastic lymphoma (PBL) is a rare and aggressive variant of diffuse large B-cell lymphoma which is associated with HIV infection. Recently, it has also been reported in immunocompetent and solid organ transplant patients. PBL commonly presents in extranodal regions such as oral cavity, digestive tract, and skin. Orbital involvement by PBL is extremely rare with only few reports in the literature. We present a case of PBL involving the bilateral orbits in an immunocompetent patient with 1-year follow-up on 18F-FDG PET/CT scan.

Publication types

  • Case Reports

MeSH terms

  • Fluorodeoxyglucose F18
  • HIV Infections*
  • Humans
  • Lymphoma, Large B-Cell, Diffuse* / diagnostic imaging
  • Plasmablastic Lymphoma* / diagnostic imaging
  • Positron Emission Tomography Computed Tomography


  • Fluorodeoxyglucose F18