Acquired brachial cutaneous dyschromatosis

Clin Dermatol. 2021 Mar-Apr;39(2):199-201. doi: 10.1016/j.clindermatol.2020.10.006. Epub 2020 Oct 16.


Acquired brachial cutaneous dyschromatosis (ABCD) is a relatively newly described, acquired disorder of pigmentation characterized by geographic-shaped, gray-brown, hyperpigmented patches and interspersed with hypopigmented macules, involving the dorsal aspects of the forearms in postmenopausal women. There is a suggested relationship with hypertension and antihypertensive medication intake, specifically angiotensin-converting enzyme inhibitors, or a cumulative effect of sun damage, as possible triggers. ABCD is benign, asymptomatic, and more of an esthetic concern. Topical depigmenting agents, chemical peels, and laser therapy may be helpful.

MeSH terms

  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents / therapeutic use
  • Female
  • Humans
  • Hyperpigmentation* / drug therapy
  • Hyperpigmentation* / etiology
  • Hypertension*


  • Angiotensin-Converting Enzyme Inhibitors
  • Antihypertensive Agents