Temporal Trends in Hospitalization for Lower Extremity Peripheral Artery Disease in Ontario: The Importance of Diabetes

Jean Jacob-Brassard; Mohammed Al-Omran; Mohamad A Hussain; Muhammad Mamdani; Thérèse A Stukel; Douglas S Lee; Charles de Mestral

doi:10.1016/j.cjca.2021.07.004

Temporal Trends in Hospitalization for Lower Extremity Peripheral Artery Disease in Ontario: The Importance of Diabetes

Can J Cardiol. 2021 Oct;37(10):1507-1512. doi: 10.1016/j.cjca.2021.07.004. Epub 2021 Jul 15.

Authors

Jean Jacob-Brassard¹, Mohammed Al-Omran², Mohamad A Hussain³, Muhammad Mamdani⁴, Thérèse A Stukel⁵, Douglas S Lee⁶, Charles de Mestral⁷

Affiliations

¹ Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada. Electronic address: jean.jacob.brassard@mail.utoronto.ca.
² Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada; Department of Surgery, King Saud University, Riyadh, Kingdom of Saudi Arabia.
³ Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada; Division of Vascular and Endovascular Surgery and the Centre for Surgery and Public Health, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
⁴ Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada; Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada; Data Science and Advanced Analytics, Unity Health Toronto, Toronto, Ontario, Canada.
⁵ ICES, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.
⁶ ICES, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada; Peter Munk Cardiac Centre and the Joint Department of Medical Imaging at the University Health Network, Toronto, Ontario, Canada.
⁷ Department of Surgery, University of Toronto, Toronto, Ontario, Canada; Li Ka Shing Knowledge Institute of St Michael's Hospital, Toronto, Ontario, Canada; ICES, Toronto, Ontario, Canada; Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

PMID: 34273474
DOI: 10.1016/j.cjca.2021.07.004

Abstract

We sought to assess temporal trends in peripheral artery disease (PAD)-related hospitalization rates in Ontario. Trends in quarterly rates of PAD hospitalization per 100,000 Ontarians between 2006 and 2019 were assessed using autocorrelated linear regression. Stratified analyses according to age, sex, and most responsible diagnosis code type (with vs without diabetes-specific PAD codes) were performed. From 2006 to 2019, overall PAD hospitalizations did not decrease significantly when diabetes-specific codes were included. A significant decrease was observed among women and those older than 65 years old. Future studies of PAD epidemiology and outcomes using administrative data should include diabetic angiopathy.

Publication types

Multicenter Study
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Aged
Aged, 80 and over
Diabetes Mellitus / epidemiology*
Diabetic Angiopathies / complications
Diabetic Angiopathies / epidemiology*
Female
Follow-Up Studies
Hospitalization / trends*
Humans
Lower Extremity / blood supply*
Male
Middle Aged
Morbidity / trends
Ontario / epidemiology
Peripheral Arterial Disease / epidemiology*
Peripheral Arterial Disease / etiology
Retrospective Studies
Risk Factors