Toward an asthma patient-reported outcome measure for use in digital remote monitoring

J Asthma. 2022 Aug;59(8):1697-1702. doi: 10.1080/02770903.2021.1955378. Epub 2021 Jul 29.


Objective: To develop and test a patient-reported outcome measure (PROM) for suitability in digital remote asthma symptom monitoring to identify uncontrolled asthma.

Methods: We modified a 5-item PROM that does not require a license, the asthma control measure (ACM), from a one-month to one-week lookback period, and evaluated it using the 5-item asthma control questionnaire (ACQ-5). We recruited subjects with asthma through MTurk, an online platform.

Results: In a sample of 498 subjects, the ACM identified uncontrolled asthma with sensitivity 0.99 and specificity 0.65. The two measures correlated with r = 0.81.

Conclusion: The ACM modified to a weekly lookback period can differentiate patients with well-controlled asthma from those with uncontrolled asthma. This PROM does not require a license and can be used in digital remote monitoring interventions.

Keywords: Asthma; patient-reported outcome measure; symptom monitoring.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Asthma* / diagnosis
  • Asthma* / therapy
  • Humans
  • Patient Reported Outcome Measures
  • Surveys and Questionnaires