Sternal Metastasis of Brain Meningioma - A Case Report

Anticancer Res. 2021 Aug;41(8):4039-4043. doi: 10.21873/anticanres.15204.


Background: Metastases of meningiomas are infrequent and the site of extracranial metastasis such as the bone is extremely rare.

Case report: A 75-year-old male had a history of five sessions of surgery and gamma-knife treatment for brain meningioma over a period of 29 years. He visited our hospital because he noticed a swelling in his anterior chest 2 years and 6 months after the final treatment. After an open biopsy, histopathological analysis revealed the mass to be a metastatic grade II meningioma. We resected the tumor along with the sternum, ribs, pleura, and pericardium. The patient had recurrences in the thoracic cavity and pericardium postoperatively and received radiation therapy. He also had metastasis in the abdominal cavity, which spread rapidly.

Conclusion: We report on a rare instance of metastasis to the sternum in a case of atypical meningioma, showing rapid growth and invasion after long-term treatment.

Keywords: Atypical meningioma; metastasis; rapid growth; sternum.