Emerging Concepts in the Surgical Management of Peri-Acetabular Metastatic Bone Disease

Curr Oncol. 2021 Jul 17;28(4):2731-2740. doi: 10.3390/curroncol28040238.


The pelvis is a common site of metastatic bone disease. Peri-acetabular lesions are particularly challenging and can cause severe pain, disability and pathologic fractures. Surgical management of these lesions has historically consisted of cementoplasty for contained lesions and Harrington reconstructions for larger, more destructive lesions. Due to the limitations of these procedures, a number of novel procedures have been developed to manage this challenging problem. Percutaneous techniques-including acetabular screw fixation and cementoplasty augmented with screws-have been developed to minimize surgical morbidity. Recent literature has demonstrated a reliable reduction in pain and improvement in function in appropriately selected patients. Several adjuncts to the Harrington procedure have been utilized in recent years to reduce complication rates. The use of constrained liners and dual mobility bearings have reduced the historically high dislocation rates. Cage constructs and porous tantalum implants are becoming increasingly common in the management of large bony defects and destructive lesions. With novel and evolving surgical techniques, surgeons are presented with a variety of surgical options to manage this challenging condition. Physicians must take into account the patients' overall health status, oncologic prognosis and anatomic location and extent of disease when developing an appropriate surgical plan.

Keywords: Harrington procedure; acetabular metastases; cementoplasty; peri-acetabular metastases.

MeSH terms

  • Acetabulum / surgery
  • Arthroplasty, Replacement, Hip*
  • Bone Neoplasms* / surgery
  • Humans
  • Pain
  • Prognosis