Cerebrospinal Fluid Flow Detection in Post-hemorrhagic Hydrocephalus With Novel Microvascular Imaging Modality

J Ultrasound Med. 2022 Apr;41(4):1013-1017. doi: 10.1002/jum.15781. Epub 2021 Jul 21.

Abstract

Cerebrospinal fluid flow dynamics serve as an important biomarker to guide medical and/or surgical intervention of hydrocephalus in infants. Imaging of cerebrospinal fluid flow can be assessed with magnetic resonance imaging, but routine evaluation is limited by practical challenges. We show for the first time that cerebrospinal fluid flow can be depicted using brain ultrasound by implementing highly sensitive ultrasound-based microvascular imaging technology (B-flow). This novel application could potentially expand the use of this technology beyond its current application in depiction of vascular flow pathologies in newborns.

Keywords: brain ultrasound; cerebrospinal fluid; cerebrospinal fluid flow; hydrocephalus; microvascular imaging (MVI); newborn.

Publication types

  • Case Reports

MeSH terms

  • Brain
  • Cerebrospinal Fluid
  • Head
  • Hemodynamics
  • Humans
  • Hydrocephalus* / diagnostic imaging
  • Infant
  • Infant, Newborn
  • Magnetic Resonance Imaging / methods