Vertical parasagittal hemispherotomy: a case report of postoperative mesio-temporal seizures via amygdalofugal pathway

Acta Neurochir (Wien). 2021 Oct;163(10):2833-2836. doi: 10.1007/s00701-021-04836-w. Epub 2021 Jul 21.

Abstract

Vertical parasagittal hemispherotomy (VPH) is a well-established surgical treatment which is proposed for children with widespread unilateral onset of intractable epileptic seizures. VPH allows to disconnect from a vertical transventricular approach all white matter fibers of the hemisphere around a central core including the thalamus. We present the case of a girl who underwent VPH for hemimegalencephaly in early infancy. Postoperatively, she developed unexpected seizures of mesio-temporal origin. Stereo-EEG provided arguments for an amygdalar origin. High-resolution MRI with tractography confirmed the presence of the amygdalo-fugal pathway to be responsible of epileptic discharges propagation. She became seizure-free after temporal resection.

Keywords: Amygdalofugal pathway; Functionnal MRI; Functionnal SEEG; Vertical Hemispherotomy; outcome.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Drug Resistant Epilepsy* / diagnostic imaging
  • Drug Resistant Epilepsy* / surgery
  • Electroencephalography
  • Epilepsy* / surgery
  • Female
  • Hemispherectomy*
  • Humans
  • Magnetic Resonance Imaging
  • Seizures / etiology
  • Seizures / surgery
  • Treatment Outcome