An academic hospital experience screening mRNA COVID-19 vaccine risk using patient allergy history

doi:10.1016/j.jaip.2021.07.010

. 2021 Oct;9(10):3807-3810.

doi: 10.1016/j.jaip.2021.07.010. Epub 2021 Jul 19.

An academic hospital experience screening mRNA COVID-19 vaccine risk using patient allergy history

Affiliations

¹ Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
² Vanderbilt Occupational Health Clinic, Vanderbilt Health & Wellness, Vanderbilt University Medical Center, Nashville, Tenn; Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
³ Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn. Electronic address: elizabeth.j.phillips@vanderbilt.edu.

PMID: 34293499
PMCID: PMC8288228
DOI: 10.1016/j.jaip.2021.07.010

An academic hospital experience screening mRNA COVID-19 vaccine risk using patient allergy history

Matthew S Krantz et al. J Allergy Clin Immunol Pract. 2021 Oct.

. 2021 Oct;9(10):3807-3810.

doi: 10.1016/j.jaip.2021.07.010. Epub 2021 Jul 19.

Affiliations

¹ Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
² Vanderbilt Occupational Health Clinic, Vanderbilt Health & Wellness, Vanderbilt University Medical Center, Nashville, Tenn; Division of General Internal Medicine and Public Health, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn.
³ Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tenn. Electronic address: elizabeth.j.phillips@vanderbilt.edu.

PMID: 34293499
PMCID: PMC8288228
DOI: 10.1016/j.jaip.2021.07.010

No abstract available

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Figures

**Figure 1**
Screening algorithm for patients with low- (green), moderate- (yellow), and high-risk (orange) allergy history and contraindication to vaccination (red).

**Figure 2**
Flowchart of the study. *PEG*, Polyethylene glycol.

See this image and copyright information in PMC

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Vaccination counseling with and without excipient skin testing in patients with suspected allergic reactions to mRNA COVID-19 vaccines and patients with atopy.
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References

1. Shimabukuro T.T., Cole M., Su J.R. Reports of anaphylaxis after receipt of mRNA COVID-19 vaccines in the US—December 14, 2020-January 18, 2021. JAMA. 2021;325:1101–1102. - PMC - PubMed
1. Cabanillas B., Akdis C., Novak N. Allergic reactions to the first COVID-19 vaccine: a potential role of polyethylene glycol? Allergy. 2021;76:1617–1618. - PubMed
1. Stone C.A., Liu Y., Relling M.V., Krantz M.S., Pratt A.L., Abreo A. Immediate hypersensitivity to polyethylene glycols and polysorbates: more common than we have recognized. J Allergy Clin Immunol Pract. 2019;7 1533-40.e8. - PMC - PubMed
1. Zhou Z.-H., Stone C.A., Jakubovic B., Phillips E.J., Sussman G., Park J. Anti-PEG IgE in anaphylaxis associated with polyethylene glycol. J Allergy Clin Immunol Pract. 2021;9 1731-33.e3. - PMC - PubMed
1. Tennessee Department of Health COVID-19 vaccination plan; March 8, 2021. https://www.tn.gov/content/dam/tn/health/documents/cedep/novel-coronavir... Available from:

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[1] Shimabukuro T.T., Cole M., Su J.R. Reports of anaphylaxis after receipt of mRNA COVID-19 vaccines in the US—December 14, 2020-January 18, 2021. JAMA. 2021;325:1101–1102. - PMC - PubMed

[2] Shimabukuro T.T., Cole M., Su J.R. Reports of anaphylaxis after receipt of mRNA COVID-19 vaccines in the US—December 14, 2020-January 18, 2021. JAMA. 2021;325:1101–1102. - PMC - PubMed

[3] Cabanillas B., Akdis C., Novak N. Allergic reactions to the first COVID-19 vaccine: a potential role of polyethylene glycol? Allergy. 2021;76:1617–1618. - PubMed

[4] Cabanillas B., Akdis C., Novak N. Allergic reactions to the first COVID-19 vaccine: a potential role of polyethylene glycol? Allergy. 2021;76:1617–1618. - PubMed

[5] Stone C.A., Liu Y., Relling M.V., Krantz M.S., Pratt A.L., Abreo A. Immediate hypersensitivity to polyethylene glycols and polysorbates: more common than we have recognized. J Allergy Clin Immunol Pract. 2019;7 1533-40.e8. - PMC - PubMed

[6] Stone C.A., Liu Y., Relling M.V., Krantz M.S., Pratt A.L., Abreo A. Immediate hypersensitivity to polyethylene glycols and polysorbates: more common than we have recognized. J Allergy Clin Immunol Pract. 2019;7 1533-40.e8. - PMC - PubMed

[7] Zhou Z.-H., Stone C.A., Jakubovic B., Phillips E.J., Sussman G., Park J. Anti-PEG IgE in anaphylaxis associated with polyethylene glycol. J Allergy Clin Immunol Pract. 2021;9 1731-33.e3. - PMC - PubMed

[8] Zhou Z.-H., Stone C.A., Jakubovic B., Phillips E.J., Sussman G., Park J. Anti-PEG IgE in anaphylaxis associated with polyethylene glycol. J Allergy Clin Immunol Pract. 2021;9 1731-33.e3. - PMC - PubMed

[9] Tennessee Department of Health COVID-19 vaccination plan; March 8, 2021. https://www.tn.gov/content/dam/tn/health/documents/cedep/novel-coronavir... Available from:

[10] Tennessee Department of Health COVID-19 vaccination plan; March 8, 2021. https://www.tn.gov/content/dam/tn/health/documents/cedep/novel-coronavir... Available from:

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An academic hospital experience screening mRNA COVID-19 vaccine risk using patient allergy history

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An academic hospital experience screening mRNA COVID-19 vaccine risk using patient allergy history

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