Anatomic Approach to Transseptal Puncture for Structural Heart Interventions

JACC Cardiovasc Interv. 2021 Jul 26;14(14):1509-1522. doi: 10.1016/j.jcin.2021.04.037.


The use of transseptal puncture continues to rise given the increase in left atrial cardiac interventions. The authors review an anatomic approach to transseptal puncture incorporating multimodality imaging both pre- and intraprocedurally with stepwise escalation algorithms to ensure safe and efficacious large-bore transseptal puncture.

Keywords: anatomic approach; left atrial intervention; structural heart disease; transseptal puncture.

Publication types

  • Review

MeSH terms

  • Atrial Fibrillation* / surgery
  • Cardiac Catheterization / adverse effects
  • Cardiac Surgical Procedures*
  • Catheter Ablation*
  • Heart Atria / diagnostic imaging
  • Heart Atria / surgery
  • Humans
  • Punctures
  • Treatment Outcome