Integrase Strand Transfer Inhibitors and Weight Gain in Children and Youth With Perinatal Human Immunodeficiency Virus in the DC Cohort

Open Forum Infect Dis. 2021 Jul 1;8(7):ofab308. doi: 10.1093/ofid/ofab308. eCollection 2021 Jul.


We conducted a retrospective analysis of 38 children and youth with human immunodeficiency virus (aged 0-19 years) in the United States and report an increased rate of change of BMI-for-age z score after initiating integrase strand transfer inhibitors (+0.19 z score units/year [95% confidence interval, .01-.37]; P = .036) for a median follow-up of 527.5 days.

Keywords: HIV; adolescents; body mass index; integrase inhibitors; youth.