Expecting the Expected: Planning Considerations for Cleanroom Construction

Int J Pharm Compd. 2021 Jul-Aug;25(4):276-281.


With a recent emphasis on sterile compounding regulatory requirements, a newly constructed space or renovations to an existing space may need to be considered in any pharmacy where sterile compounding occurs. Pharmacy leaders from two facilities within a health system outline their experience with important aspects of cleanroom renovation learned through the process. Identifying how to maintain sterile compounding operations during construction is required to continue patient-care services. The collaboration of several disciplines on a construction team will help ensure the new/ renovated space has the necessary components to eventually support compounding sterile preparations. Through thorough understanding of the proposed changes of sterile compounding regulatory requirements and extensive planning, a successful renovation and go-live coordination can occur. This article serves to summarize key takeaways from two pharmacy leaders' cleanroom construction experiences.

MeSH terms

  • Drug Compounding
  • Environment, Controlled
  • Humans
  • Patient Care
  • Pharmacy Service, Hospital*
  • Pharmacy*