Activity observed in biological neural networks is determined by anatomical connectivity between cortical areas. The monkey frontoparietal network facilitates cognitive functions, but the organization of its connectivity is unknown. Here, a new connectivity matrix is proposed which shows that the network utilizes a small-world architecture and the 3-node M9 motif. Its areas exhibit relatively homogeneous connectivity with no suggestion of the hubs seen in scale-free networks. Crucially, its M9 dynamical relay motif is optimally arranged for near-zero and non-zero phase synchrony to arise in support of cognition, serving as a candidate topological mechanism for previously reported findings. These results can serve as a benchmark to be used in the treatment of neurological disorders where the types of cognition the frontoparietal network supports are impaired.
Keywords: Computational neuroscience; Macaque; Network neuroscience; Neural network; Small-world; Synchrony.
Copyright © 2021. Published by Elsevier Inc.