Neuropathic pain post-COVID-19: a case report

BMJ Case Rep. 2021 Jul 22;14(7):e243459. doi: 10.1136/bcr-2021-243459.


A 61-year-old man with no significant medical history developed fever, headache and mild shortness of breath. He tested positive for SARS-CoV-2 and self-isolated at home, not requiring hospital admission. One week after testing positive, he developed acute severe burning pain affecting his whole body, subsequently localised distally in the limbs. There was no ataxia or autonomic failure. Neurological examination was unremarkable. Electrophysiological tests were unremarkable. Skin biopsy, lumbar puncture, enhanced MRI of the brachial plexus and MRI of the neuroaxis were normal. His pain was inadequately controlled with pregabalin but improved while on a weaning regimen of steroids. This case highlights the variety of possible symptoms associated with SARS-CoV-2 infection.

Keywords: COVID-19; neurology; pain (neurology).

Publication types

  • Case Reports

MeSH terms

  • COVID-19*
  • Fever
  • Hospitalization
  • Humans
  • Male
  • Middle Aged
  • Neuralgia* / diagnosis
  • Neuralgia* / drug therapy
  • Neuralgia* / etiology
  • SARS-CoV-2