Implications of Adverse Biological Factors and Management of Solitary Fibrous Tumors of the Pleura

Weston G Andrews; Eric Vallières

doi:10.1016/j.thorsurg.2021.04.009

Implications of Adverse Biological Factors and Management of Solitary Fibrous Tumors of the Pleura

Thorac Surg Clin. 2021 Aug;31(3):347-355. doi: 10.1016/j.thorsurg.2021.04.009. Epub 2021 Jun 9.

Authors

Weston G Andrews¹, Eric Vallières²

Affiliations

¹ Swedish Cancer Institute, 1101 Madison Street, Suite 900, Seattle, WA 98104, USA.
² Division of Thoracic Surgery, Swedish Cancer Institute, 1101 Madison Street, Suite 900, Seattle, WA 98104, USA. Electronic address: Eric.Vallieres@swedish.org.

PMID: 34304844
DOI: 10.1016/j.thorsurg.2021.04.009

Abstract

Solitary fibrous tumors arise in many locations throughout the body and are genetically and histologically considered a single disease. Solitary fibrous tumors of the pleura (SFTP) are the most common tumor of this disease. Most of the SFTPs are treated with surgery alone, and chemotherapy and radiotherapy do not seem to play a role in treatment. Tumor size and unfavorable histology are risk factors for malignant potential. Incomplete resection is an important risk factor for recurrence.

Keywords: CD-34; Mesenchymal tumor; NAB2-STAT6 fusion gene; Pleural tumor; Solitary fibrous tumors of the pleura.

Publication types

Review

MeSH terms

Biological Factors
Humans
Neoplasm Recurrence, Local
Pleura*
Solitary Fibrous Tumor, Pleural* / diagnostic imaging
Solitary Fibrous Tumor, Pleural* / surgery

Substances

Biological Factors