Implications of Adverse Biological Factors and Management of Solitary Fibrous Tumors of the Pleura

Thorac Surg Clin. 2021 Aug;31(3):347-355. doi: 10.1016/j.thorsurg.2021.04.009. Epub 2021 Jun 9.


Solitary fibrous tumors arise in many locations throughout the body and are genetically and histologically considered a single disease. Solitary fibrous tumors of the pleura (SFTP) are the most common tumor of this disease. Most of the SFTPs are treated with surgery alone, and chemotherapy and radiotherapy do not seem to play a role in treatment. Tumor size and unfavorable histology are risk factors for malignant potential. Incomplete resection is an important risk factor for recurrence.

Keywords: CD-34; Mesenchymal tumor; NAB2-STAT6 fusion gene; Pleural tumor; Solitary fibrous tumors of the pleura.

Publication types

  • Review

MeSH terms

  • Biological Factors
  • Humans
  • Neoplasm Recurrence, Local
  • Pleura*
  • Solitary Fibrous Tumor, Pleural* / diagnostic imaging
  • Solitary Fibrous Tumor, Pleural* / surgery


  • Biological Factors