The Potential Role of Korean Mistletoe Extract as an Anti-Inflammatory Supplementation

J Immunol Res. 2021 Jun 29:2021:2183427. doi: 10.1155/2021/2183427. eCollection 2021.

Abstract

Korean mistletoe has anti-inflammatory and antioxidant functions and may be a useful training supplement. We investigated the effect of Korean mistletoe extract (KME) on inflammatory markers after high-intensity exercise by 20 university male rowers (KME group vs. CON group) consuming 110 mL KME/dose (2 times a day over 8 weeks). Blood samples were collected for measurement of serum cytokine levels at baseline, immediately after exercise, and following 30 minutes of recovery. Interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-α), and C-reactive protein (CRP) were used as markers for inflammation. After supplementation, IL-6 and TNF-α levels were significantly lowered in the KME group than in the CON group at baseline, immediately after exercise, and following 30 minutes of recovery. KME can reduce high-strength exercise-induced increases in the levels of serum inflammatory cytokines in active individuals and improve anti-inflammatory functions.

Publication types

  • Clinical Trial

MeSH terms

  • Anti-Inflammatory Agents / administration & dosage*
  • Athletes
  • Biomarkers / blood
  • Dietary Supplements*
  • Humans
  • Inflammation / blood
  • Inflammation / diagnosis
  • Inflammation / immunology
  • Inflammation / prevention & control*
  • Inflammation Mediators / blood
  • Male
  • Mistletoe / chemistry*
  • Plant Extracts / administration & dosage*
  • Republic of Korea
  • Resistance Training
  • Water Sports
  • Young Adult

Substances

  • Anti-Inflammatory Agents
  • Biomarkers
  • Inflammation Mediators
  • Plant Extracts