Neurobiology: Resetting the axon's batteries

Curr Biol. 2021 Jul 26;31(14):R914-R917. doi: 10.1016/j.cub.2021.06.014.


Neuronal injury can cause mitochondrial damage, leading to reduced energy production, decreased Ca2+ storage capacity, and increased reactive oxygen species. A new study reveals a mechanism to trigger the axonal transport of previously anchored mitochondria and promote neuroprotection and axon regeneration by replacing damaged with functional mitochondria.

Publication types

  • Comment

MeSH terms

  • Axonal Transport
  • Axons* / metabolism
  • Nerve Regeneration*
  • Neurobiology
  • Neurons