Eosinophilic Granulomatosis With Polyangiitis Presenting as an Acute Coronary Syndrome

Jeffrey Kolominsky; Zackary Tushak; Jaideep Patel; Aaron Schatz; Ajay Pillai; Jonathan Potfay

doi:10.1016/j.jaccas.2020.05.001

Eosinophilic Granulomatosis With Polyangiitis Presenting as an Acute Coronary Syndrome

JACC Case Rep. 2020 Jun 17;2(7):1062-1065. doi: 10.1016/j.jaccas.2020.05.001.

Authors

Jeffrey Kolominsky¹, Zackary Tushak², Jaideep Patel², Aaron Schatz², Ajay Pillai², Jonathan Potfay³

Affiliations

¹ Department of Medicine, Virginia Commonwealth University Health System, Richmond, Virginia.
² Division of Cardiology, Pauley Heart Center, Virginia Commonwealth University Medical Center, Richmond, Virginia.
³ Division of Cardiology, Hunter Holmes McGuire Veteran Medical Center, Richmond, Virginia.

Abstract

Eosinophilic granulomatosis with polyangiitis, formerly Churg-Strauss Syndrome, is an uncommon disorder that carries a high mortality when coronary artery disease develops. Early recognition and treatment is crucial. We highlight an unusual presentation of acute coronary syndrome not associated with atherosclerotic coronary disease. (Level of Difficulty: Intermediate.).

Keywords: ANCA, antineutrophilic cytoplasmic antibody; CA, coronary angiograph; CABG, coronary artery bypass graft; CRP, C-reactive protein; DES, drug-eluting stent; EGPA; EGPA, eosinophilic granulomatosis with polyangiitis; ESR, erythrocyte sedimentation rate; LAD, left anterior descending artery; LCx, left circumflex artery; LMCA, left main coronary artery; OM1, obtuse marginal artery; R-PLB, right posterior-lateral branch; RCA, right coronary artery; acute coronary syndrome; eosinophilia; ischemic heart disease; premature coronary artery disease; vasculitis.

Publication types

Case Reports