Low back and leg pain may be due to many causes including scarring in the epidural space. Scar tissue often causes irritated swollen and inflamed nerves, which can cause pain. Adhesiolysis eliminate the pain-causing effects of scar tissue by releasing or decompression of a nerve from scar tissue. Percutaneous adhesiolysis is a safe and effective procedure, while epiduroscopy is a minimally invasive technique that offers diagnostic and therapeutic advantages in cases of chronic low back pain and radiculopathy. The aim of this review is to describe the comparison of percutaneous and endoscopic procedures in the lysis of adhesions in epidural fibrosis in terms of indications, contraindications, complications, technique and efficacy..