Amblyopia risk factors among pediatric patients in a hospital-based setting using photoscreening

PLoS One. 2021 Jul 29;16(7):e0254831. doi: 10.1371/journal.pone.0254831. eCollection 2021.

Abstract

Purpose: The aim of our study was to determine the prevalence of amblyopia risk factors in children visiting the American University of Beirut Medical Center (AUBMC) using automated vision screening.

Methods: This was a hospital-based screening of 1102 children aged between 2 and 6 years. Vision screening was performed using PlusoptiX S12 over 2 years (2018-2020). The need for referral to a pediatric ophthalmologist was based on the amblyopia risk factors set forth by the American Association for Pediatric Ophthalmology and Strabismus. Referred patients underwent a comprehensive eye examination.

Results: A total of 1102 children were screened, 63 were referred for amblyopia risk factors (5.7%); 37/63 (59%) underwent comprehensive eye examination and 73% were prescribed glasses. Of the non-referred group of children, 6.35% had astigmatism, 6.25% were hyperopic and 3.27% were myopic. The refractive errors observed among the examined patients were distributed as follows: 41% astigmatism, 51% hyperopia, and 8% myopia; amblyopia was not detected. Refractive amblyopia risk factors were associated with the presence of systemic disorders. Bland-Altman plots showed most of the differences to be within limits of agreement.

Conclusion: Using an automated vision screener in a hospital-based cohort of children aged 2 to 6 years, the rate of refractive amblyopia risk factors was 5.7%. Hyperopia was the most commonly encountered refractive error and children with systemic disorders were at higher risk.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amblyopia*
  • Child
  • Child, Preschool
  • Humans
  • Male
  • Prevalence
  • Referral and Consultation
  • Risk Factors
  • Vision Screening*

Grants and funding

This study was funded by the Medical Practice Plan (MPP) of the American University of Beirut awarded to CA (https://www.aub.edu.lb/fm/medicalresearch/Pages/ResearchFunding.aspx). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.