Guidance on the limits to the number of embryos to transfer: a committee opinion

Fertil Steril. 2021 Sep;116(3):651-654. doi: 10.1016/j.fertnstert.2021.06.050. Epub 2021 Jul 28.


On the basis of American Society for Reproductive Medicine and Society for Assisted Reproductive Technology data, the American Society for Reproductive Medicine's guidelines for the limits on the number of embryos to be transferred during in vitro fertilization cycles have been further refined in continuing efforts to promote singleton gestation and reduce the number of multiple pregnancies. This version replaces the document titled "Criteria for number of embryos to transfer: a committee opinion" that was published most recently in August of 2017 (Fertil Steril 2017;107:901-3).

Keywords: Assisted reproduction; IVF; blastocyst; euploid; transfer.

Publication types

  • Practice Guideline

MeSH terms

  • Adult
  • Clinical Decision-Making
  • Consensus
  • Embryo Transfer / adverse effects
  • Embryo Transfer / standards*
  • Female
  • Fertilization in Vitro / adverse effects
  • Fertilization in Vitro / standards*
  • Humans
  • Infertility / diagnosis
  • Infertility / physiopathology
  • Infertility / therapy*
  • Maternal Age
  • Pregnancy
  • Pregnancy Reduction, Multifetal / standards
  • Reproductive Medicine / standards*
  • Risk Assessment
  • Risk Factors
  • Single Embryo Transfer / standards
  • Treatment Outcome