Collision Tumors of Gastric Adenocarcinoma and Mucosa-associated Lymphoid Tissue Lymphoma

Intern Med. 2021;60(15):2419-2424. doi: 10.2169/internalmedicine.6124-20. Epub 2021 Aug 1.

Abstract

A 65-year-old woman with a history of treatment for splenic marginal zone B-cell lymphoma and gastric mucosa-associated lymphoid tissue (MALT) lymphoma underwent esophagogastroduodenoscopy. A reddish elevated lesion was found in the fundus of the stomach. On image-enhanced endoscopy, several findings, such as glandular structures of varying sizes suggesting well-differentiated adenocarcinoma, pruned blood vessels, and dilated blood vessels in deeper mucosa suggesting MALT lymphoma, were observed. The final pathological diagnosis after surgical resection was collision tumors of well-differentiated adenocarcinoma and MALT lymphoma. The features of both tumors could be observed simultaneously with image-enhanced endoscopy.

Keywords: collision tumor; double tumor; gastric adenocarcinoma; image enhanced endoscopy; mucosa-associated lymphoid tissue lymphoma.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma* / diagnostic imaging
  • Adenocarcinoma* / surgery
  • Aged
  • Endoscopy, Digestive System
  • Female
  • Gastric Mucosa
  • Helicobacter Infections*
  • Helicobacter pylori*
  • Humans
  • Lymphoma, B-Cell, Marginal Zone* / diagnostic imaging
  • Stomach Neoplasms* / diagnostic imaging
  • Stomach Neoplasms* / surgery