PTPMT1 Is Required for Embryonic Cardiac Cardiolipin Biosynthesis to Regulate Mitochondrial Morphogenesis and Heart Development

Circulation. 2021 Aug 3;144(5):403-406. doi: 10.1161/CIRCULATIONAHA.121.054768. Epub 2021 Aug 2.
No abstract available

Keywords: cardiolipins; mitochondria; mitochondrial membranes; myocytes, cardiac; protein tyrosine phosphatases.

Publication types

  • Letter
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cardiolipins / biosynthesis
  • Cardiolipins / genetics*
  • Gene Expression Profiling
  • Gene Expression Regulation, Developmental
  • Heart / embryology*
  • Immunohistochemistry
  • Mice
  • Mitochondria, Heart / genetics*
  • Mitochondria, Heart / metabolism*
  • Morphogenesis / genetics*
  • Organogenesis / genetics*
  • PTEN Phosphohydrolase / genetics*

Substances

  • Cardiolipins
  • Ptpmt1 protein, mouse
  • PTEN Phosphohydrolase