Impact of the human leucocyte antigen (HLA)-B leader peptide dimorphism and HLA-A expression on outcomes of stem cell transplantation for sickle cell disease

Br J Haematol. 2021 Oct;195(2):e128-e131. doi: 10.1111/bjh.17665. Epub 2021 Aug 2.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anemia, Sickle Cell / immunology*
  • Anemia, Sickle Cell / therapy
  • Case-Control Studies
  • Graft vs Host Disease / immunology
  • HLA-A Antigens / genetics*
  • HLA-A Antigens / metabolism
  • HLA-B Antigens / genetics*
  • HLA-B Antigens / metabolism
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Immunity / immunology
  • Immunotherapy / methods
  • Interleukin-2 / immunology
  • Interleukin-2 / therapeutic use
  • Killer Cells, Natural / immunology
  • Methionine
  • Polymorphism, Single Nucleotide
  • Protein Sorting Signals / genetics*
  • Sex Characteristics
  • Threonine
  • Treatment Outcome

Substances

  • HLA-A Antigens
  • HLA-B Antigens
  • Interleukin-2
  • Protein Sorting Signals
  • Threonine
  • Methionine