[Pulmonary carcinosarcoma with ALK gene rearrangement: report of a case]

Z H Lin; X B Qiu; J T Fu; D H Gan

doi:10.3760/cma.j.cn112151-20201215-00930

[Pulmonary carcinosarcoma with ALK gene rearrangement: report of a case]

Zhonghua Bing Li Xue Za Zhi. 2021 Aug 8;50(8):951-953. doi: 10.3760/cma.j.cn112151-20201215-00930.

[Article in Chinese]

Authors

Z H Lin¹, X B Qiu², J T Fu¹, D H Gan¹

Affiliations

¹ Department of Pathology, the First Affiliated Hospital of Jinan University, Guangzhou 510000, China.
² Wuhan Kindstar Diagnostics Co., Wuhan 430000, China.

PMID: 34344086
DOI: 10.3760/cma.j.cn112151-20201215-00930

Abstract

肺癌肉瘤是肺肉瘤样癌的一种组织学亚型，发病率低，具有高度侵袭性，易于复发和转移。该文报道1例53岁女性原发性肺癌肉瘤病例，为肺腺癌和未分化肉瘤两种成分混合。分子检测显示间变性淋巴瘤激酶（ALK）基因重排。总结其临床病理学特征、组织形态和免疫表型、诊断与鉴别诊断，以及分子生物学特征，以提高对本病的认识。.

Publication types

Case Reports

MeSH terms

Anaplastic Lymphoma Kinase / genetics
Carcinosarcoma* / genetics
Gene Rearrangement
Humans
Lung Neoplasms* / genetics

Substances

Anaplastic Lymphoma Kinase