Efficacy of Gamma Knife radiosurgery in the management of pituitary prolactinoma

Bassam Mahmood Flamerz Arkawazi; Ahmed Al Atraqchi; Arjan Adnan; Shaymaa Dheyab

doi:10.25259/SNI_230_2021

Efficacy of Gamma Knife radiosurgery in the management of pituitary prolactinoma

Surg Neurol Int. 2021 Jul 19:12:357. doi: 10.25259/SNI_230_2021. eCollection 2021.

Authors

Bassam Mahmood Flamerz Arkawazi¹, Ahmed Al Atraqchi², Arjan Adnan², Shaymaa Dheyab³

Affiliations

¹ Department of Surgery, Alkindy College of Medicine, University of Baghdad.
² Department of Neurosurgery, Neurosciences Hospital, Baghdad, Iraq.
³ Department of Laboratory, Alyarmouk Teaching Hospital, Baghdad, Iraq.

Abstract

Background: Gamma Knife radiosurgery (GKR) has been widely used in the management of a variety of intracranial tumors, including pituitary adenomas. Pituitary prolactinoma (Prs) is one of the most common types of these adenomas.

Methods: This prospective study included 50 patients with pituitary Prs over a period from June 2017 to June 2018 at the Neurosciences Hospital, Baghdad/Iraq. The GKR procedure was performed using the Leksell Gamma Knife^® Perfexion™, 192 beams of Cobalt 60 radiation were delivered through the intact skull to the pituitary Prs.

Results: There is a significant female predominance 32 (72%). The results after 6 months of GKR showed significant improvement regarding the size of adenoma, prolactin hormone level, contrast enhancement on MRI, and medical treatment.

Conclusion: The study showed that the GKR is a safe and effective modality of treatment in the management of pituitary Prs.

Keywords: Gamma Knife; Pituitary adenoma; Prolactinoma; Stereotactic radiosurgery.