Adult Henoch-Schönlein nephritis

Aust N Z J Med. 1987 Aug;17(4):396-401. doi: 10.1111/j.1445-5994.1987.tb00072.x.

Abstract

A retrospective study was performed of all patients at the Royal Adelaide Hospital over a ten-year period with biopsy proven Henoch-Schönlein nephritis. The records of 27 patients were examined, with emphasis on clinical and histopathological presentation, treatment and outcome. A scheme for assessing glomerular histology is presented, and severity correlated with prognosis of the disease. At presentation unfavourable prognostic indicators were acute renal impairment, crescents in greater than 20% of glomeruli, and severe glomerular histological lesions. Four patients died as a result of the disease, and 20 of the patients had evidence of continued renal abnormality at follow-up. Adult Henoch-Schönlein nephritis is a potentially catastrophic disease, and requires careful assessment at presentation.

MeSH terms

  • Biopsy
  • Female
  • Follow-Up Studies
  • Glomerular Mesangium / pathology
  • Glomerulonephritis / pathology*
  • Humans
  • Hypertension, Renal / pathology
  • Kidney Glomerulus / pathology
  • Male
  • Middle Aged
  • Proteinuria / pathology
  • Purpura, Schoenlein-Henoch / pathology*