Acute viral encephalitis in children

Aust Paediatr J. 1987 Dec;23(6):339-42. doi: 10.1111/j.1440-1754.1987.tb00286.x.

Abstract

Fifty-seven cases satisfying criteria of the diagnosis of acute viral encephalitis were studied. They were divided into two groups: Group 1 (presumed), 48 cases; Group 2 (postinfectious), nine cases. A possible association of viral aetiology was found in 26%. Viruses isolated were: influenza (3 cases), Coxsackie virus (2), adenovirus (2), mixed cytomegalovirus and adenovirus and herpes simplex viruses (1 case each). The mortality rate was 28%. Among the 41 survivors, 76% were completely normal and 24% had neurological sequelae with focal neurological deficit in 29%; personality changes in 6%; moderate mental retardation in 2%; severe mental retardation in 4%; hyperactivity in 4% and epilepsy in 4%. The best predictors to unfavourable outcome were the rapid rate of deterioration in conscious level after admission and the age of the patients.

MeSH terms

  • Acute Disease
  • Age Factors
  • Child
  • Child, Preschool
  • Electroencephalography
  • Encephalitis / cerebrospinal fluid
  • Encephalitis / diagnosis
  • Encephalitis / etiology*
  • Encephalitis / microbiology
  • Encephalitis / mortality
  • Encephalitis Viruses / isolation & purification
  • Follow-Up Studies
  • Humans
  • Infant
  • Prognosis
  • Retrospective Studies
  • Tomography, X-Ray Computed