Survival in systemic lupus erythematosus. A multivariate analysis of demographic factors

Arthritis Rheum. 1987 Dec;30(12):1326-32. doi: 10.1002/art.1780301202.


We analyzed survival rate and important clinical outcomes in 411 patients with systemic lupus erythematosus who were seen at our center between 1969 and 1984. All eligible subjects met 4 of the revised American Rheumatism Association criteria for systemic lupus erythematosus and all were seen within 2 years of diagnosis. Mean followup was 75.6 months. Multivariate analysis suggested significant independent effects of race (P = 0.0139) and socioeconomic status (P = 0.0326) on survival. No evidence of diminished lupus-related mortality with age was documented. Previously reported findings of improved survival rate with age may have been confounded by differences in race distribution between the younger- and older-onset groups.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Age Factors
  • Female
  • Humans
  • Lupus Erythematosus, Systemic / mortality*
  • Male
  • Middle Aged
  • Racial Groups
  • Risk Factors
  • Sex Factors
  • Socioeconomic Factors