Metacarpophalangeal arthropathy associated with manual labor (Missouri metacarpal syndrome). Clinical radiographic, and pathologic characteristics of an unusual degeneration process

Arthritis Rheum. 1987 Dec;30(12):1362-71. doi: 10.1002/art.1780301207.

Abstract

We describe 7 manual laborers with painful, palpably enlarged metacarpophalangeal joints. Characteristic radiographic changes were joint space loss, prominent osteophytes, and cystic metacarpal heads most prominent in the second and third metacarpophalangeal joints. In 3 of 4 patients, joint biopsy specimens showed subsynovial fibrosis and villous hyperplasia. All 7 patients had similar backgrounds of heavy work demanding sustained gripping motions of both hands, for periods that exceeded 30 years. We designated their condition metacarpophalangeal arthropathy associated with manual labor.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Aged
  • Biopsy
  • Cumulative Trauma Disorders* / diagnosis
  • Cumulative Trauma Disorders* / diagnostic imaging
  • Cumulative Trauma Disorders* / pathology
  • Finger Joint* / diagnostic imaging
  • Finger Joint* / pathology
  • Humans
  • Joint Diseases / diagnosis
  • Joint Diseases / diagnostic imaging
  • Joint Diseases / pathology
  • Male
  • Metacarpophalangeal Joint* / diagnostic imaging
  • Metacarpophalangeal Joint* / pathology
  • Middle Aged
  • Occupational Diseases* / diagnosis
  • Occupational Diseases* / diagnostic imaging
  • Occupational Diseases* / pathology
  • Occupations
  • Radiography
  • Syndrome
  • Synovial Membrane / pathology