Detection of Cytomegalovirus in Urine Dried on Filter Paper

J Pediatric Infect Dis Soc. 2021 Nov 11;10(10):958-961. doi: 10.1093/jpids/piab033.

Abstract

Urine is the best specimen for the diagnosis of congenital cytomegalovirus, but collection and processing of liquid urine are impractical for screening. Urine dried on filter paper was processed by the same convenient, low-cost method used by newborn screening to test blood spots and showed high sensitivity and specificity.

Keywords: congenital cytomegalovirus; dried urine spots; filter paper; newborn screening.

MeSH terms

  • Cytomegalovirus Infections* / diagnosis
  • Cytomegalovirus* / genetics
  • DNA, Viral
  • Humans
  • Infant, Newborn
  • Neonatal Screening
  • Sensitivity and Specificity

Substances

  • DNA, Viral