Genome structure and genetic diversity in the Ebola virus

Curr Opin Pharmacol. 2021 Oct:60:83-90. doi: 10.1016/j.coph.2021.06.010. Epub 2021 Aug 4.

Abstract

Ebola is a deadly pathogen responsible for Ebola virus disease, first came to prominence in the year 1976. This rapidly evolving virus imposed a serious threat to the human population in the last few decades and also continues to be a probable threat to our race. A better understanding of the virus in terms of its genomic structure is very much needed to develop an effective antiviral therapy against this deadly pathogen. Complete knowledge of its genomic structure and variations will help us and the entire scientific community to design effective therapy in terms of either vaccine development or the development of proper antiviral medicine.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / pharmacology
  • Antiviral Agents / therapeutic use
  • Ebolavirus* / genetics
  • Genetic Variation
  • Genomics
  • Hemorrhagic Fever, Ebola* / drug therapy
  • Humans

Substances

  • Antiviral Agents