Characterization of chitosan film with cinnamon essential oil emulsion co-stabilized by ethyl-Nα-lauroyl-l-arginate hydrochloride and hydroxypropyl-β-cyclodextrin

Int J Biol Macromol. 2021 Oct 1:188:24-31. doi: 10.1016/j.ijbiomac.2021.08.007. Epub 2021 Aug 5.

Abstract

To improve the antimicrobial properties of chitosan films, cinnamon essential oil (CEO) nanoemulsion (1% and 3% v/v CEO) stabilized by ethyl-Nα-lauroyl-l-arginate hydrochloride (LAE) alone or co-stabilized by LAE and hydroxypropyl-β-cyclodextrin (HPCD) were incorporated into chitosan matrix. The micromorphology, physical and antimicrobial properties of the composite films were compared. The dense structure of the CEO nanoemulsion co-stabilized by LAE and HPCD reduced the water vapor permeability and water content. The incorporation of the CEO nanoemulsion co-stabilized by LAE and HPCD, reduced the adverse effects of CEO on the mechanical properties and microstructure of the film, and even slightly increased the tensile strength. In addition, the antimicrobial properties of chitosan films were enhanced due to the encapsulation and emulsification effect of HPCD and LAE on CEO. This work indicated that the prepared chitosan based edible films had the potential to be used in the field of food packaging to improve food safety.

Keywords: Antimicrobial property; Chitosan film; Cinnamon essential oil nanoemulsion; Ethyl-N(α)-lauroyl-l-arginate hydrochloride; Hydroxypropyl-β-cyclodextrin.

MeSH terms

  • 2-Hydroxypropyl-beta-cyclodextrin / chemistry
  • 2-Hydroxypropyl-beta-cyclodextrin / pharmacology
  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology
  • Arginine / analogs & derivatives
  • Arginine / chemistry
  • Arginine / pharmacology
  • Bacteria / drug effects*
  • Bacteria / pathogenicity
  • Chitosan / chemistry*
  • Chitosan / pharmacology
  • Cinnamomum zeylanicum / chemistry*
  • Emulsions / chemistry
  • Emulsions / pharmacology
  • Food Packaging
  • Humans
  • Microbial Sensitivity Tests
  • Oils, Volatile / chemistry*
  • Oils, Volatile / pharmacology
  • Water / chemistry

Substances

  • Anti-Infective Agents
  • Emulsions
  • Oils, Volatile
  • ethyl-N(alpha)-dodecanoyl-L-arginate
  • Water
  • 2-Hydroxypropyl-beta-cyclodextrin
  • Chitosan
  • Arginine