An overview of healthcare-associated infections in a tertiary care hospital in Egypt

Rania Hassan; Abdel-Hady El-Gilany; Amina M Abd Elaal; Noha El-Mashad; Dalia Abdel Azim

doi:10.1016/j.infpip.2020.100059

An overview of healthcare-associated infections in a tertiary care hospital in Egypt

Infect Prev Pract. 2020 May 19;2(3):100059. doi: 10.1016/j.infpip.2020.100059. eCollection 2020 Sep.

Authors

Rania Hassan¹, Abdel-Hady El-Gilany², Amina M Abd Elaal³, Noha El-Mashad³, Dalia Abdel Azim⁴

Affiliations

¹ Clinical Pathology, Ministry of Health, Egypt.
² Public Health & Preventive Medicine, Faculty of Medicine, Mansoura University, Egypt.
³ Clinical Pathology, Faculty of Medicine, Mansoura University, Egypt.
⁴ Director of Molecular Genetics, Department of Pathology, NYU Winthrop University Hospital, USA.

Abstract

Background: Healthcare-associated infection (HAI) is a major problem in healthcare facilities and is associated with increased morbidity and mortality and prolonged hospital stay. This study aims to determine the incidence rate, risk factors, and bacterial aetiology of HAI in a tertiary care hospital in Mansoura, Egypt.

Methods: This is a prospective observational study carried out over 12 months in different departments of Mansoura New General Hospital (MNGH). Data were collected from patient's records and laboratory results of the ongoing HAI surveillance program.

Results: The incidence of HAI was 3.7% among 6912 patients studied. The independent predictors of HAI were multiple devices (AOR=88.1), central venous catheter (CVC) (AOR=34), urinary catheter (AOR=28.9) and length of stay >20 days (AOR=3.1). Surgical site infections (SSI) were the most frequent (24%) followed by catheter associated urinary tract infections (CAUTI) (20%). The most frequently isolated pathogens were Klebsiella spp. (27.2%), and E. coli (18%).

Conclusions: HAI is a significant problem in MNGH. Klebsiella spp. were the predominant causative organisms of HAI, as has been described in other studies from developing countries.

Keywords: Healthcare-associated infection -risk factors-causative pathogens.