Acute abdomen in the immunocompromised patient: WSES, SIS-E, WSIS, AAST, and GAIS guidelines

World J Emerg Surg. 2021 Aug 9;16(1):40. doi: 10.1186/s13017-021-00380-1.


Immunocompromised patients are a heterogeneous and diffuse category frequently presenting to the emergency department with acute surgical diseases. Diagnosis and treatment in immunocompromised patients are often complex and must be multidisciplinary. Misdiagnosis of an acute surgical disease may be followed by increased morbidity and mortality. Delayed diagnosis and treatment of surgical disease occur; these patients may seek medical assistance late because their symptoms are often ambiguous. Also, they develop unique surgical problems that do not affect the general population. Management of this population must be multidisciplinary.This paper presents the World Society of Emergency Surgery (WSES), Surgical Infection Society Europe (SIS-E), World Surgical Infection Society (WSIS), American Association for the Surgery of Trauma (AAST), and Global Alliance for Infection in Surgery (GAIS) joined guidelines about the management of acute abdomen in immunocompromised patients.

Keywords: Anesthesia; Appendicitis; Cancer; Cholecystitis; Cytomegalovirus; Diverticulitis; Hematologic; Immunocompetence; Immunocompromise; Immunosuppression; Infections; Intra-abdominal; Leukemia; Lymphoma; Oncologic; Perforation; Perioperative; Peritonitis; Transplanted; Tuberculosis.

Publication types

  • Practice Guideline

MeSH terms

  • Abdomen, Acute / diagnosis*
  • Abdomen, Acute / mortality
  • Abdomen, Acute / surgery*
  • Emergency Service, Hospital
  • Humans
  • Immunocompromised Host*
  • Postoperative Complications / prevention & control