Tumor heterogeneity

Cancer Cell. 2021 Aug 9;39(8):1015-1017. doi: 10.1016/j.ccell.2021.07.009.


Tumor heterogeneity was traditionally considered in the genetic terms, but it has now been broadened into many more facets. These facets represent a challenge in our understanding of cancer etiology but also provide opportunity for us to understand prognosis and therapy response.

MeSH terms

  • Genetic Heterogeneity*
  • Humans
  • Lung Neoplasms* / pathology
  • Lung Neoplasms* / therapy
  • Mutation
  • Neoplasms / diagnostic imaging
  • Neoplasms / genetics*
  • Neoplasms / pathology*
  • Single-Cell Analysis
  • Small Cell Lung Carcinoma / pathology
  • Small Cell Lung Carcinoma / therapy