Pityriasis rubra pilaris-like eruption following administration of the BNT163b2 (Pfizer-BioNTech) mRNA COVID-19 vaccine

Clin Exp Dermatol. 2022 Jan;47(1):188-190. doi: 10.1111/ced.14878. Epub 2021 Sep 24.


We describe a case of a pityriasis rubra pilaris (PRP)-like eruption occurring following administration of the Pfizer-Biontech mRNA COVID-19 vaccine, with worsening of the condition following the second dose. To our knowledge, this is the first reported case of a PRP-like eruption as a cutaneous adverse event of the Pfizer-Biontech mRNA COVID-19 vaccine.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • BNT162 Vaccine / adverse effects*
  • COVID-19 / prevention & control*
  • Drug Eruptions / etiology*
  • Drug Eruptions / pathology
  • Humans
  • Male
  • Middle Aged
  • Pityriasis Rubra Pilaris / chemically induced*
  • Pityriasis Rubra Pilaris / pathology
  • SARS-CoV-2


  • BNT162 Vaccine