Purpose: To extend and validate the accuracy and efficiency of a graphics processing unit (GPU)-Monte Carlo dose engine for Elekta Unity 1.5 T Magnetic Resonance-Linear Accelerator (MR-LINAC) online independent dose verification.
Methods: Electron/positron propagation physics in a uniform magnetic field was implemented in a previously developed GPU-Monte Carlo dose engine-gDPM. The dose calculation accuracy in the magnetic field was first evaluated in heterogeneous phantom with EGSnrc. The dose engine was then commissioned to a Unity machine with a virtual two photon-source model and compared with the Monaco treatment planning system. Fifteen patient plans from five tumor sites were included for the quantification of online dose verification accuracy and efficiency.
Results: The extended gDPM accurately calculated the dose in a 1.5 T external magnetic field and was well matched with EGSnrc. The relative dose difference along central beam axis was less than 0.5% for the homogeneous region in water-lung phantom. The maximum difference was found at the build-up regions and heterogeneous interfaces, reaching 1.9% and 2.4% for 2 and 6 MeV mono-energy photon beams, respectively. The root mean square errors for depth-dose fall-off region were less than 0.2% for all field sizes and presented a good match between gDPM and Monaco GPUMCD. For in-field profiles, the dose differences were within 1% for cross-plane and in-plane directions for all calculated depths except dmax. For penumbra regions, the distance-to-agreements between two dose profiles were less than 0.1 cm. For patient plan verification, the maximum relative average dose difference was 1.3%. The gamma passing rates with criteria 3% (2 mm) for dose regions above 20% were between 93% and 98%. gDPM can complete the dose calculation for less than 40 s with 5 × 108 photons on a single NVIDIA GTX-1080Ti GPU and achieve a statistical uncertainty of 0.5%-1.1% for all evaluated cases.
Conclusions: A GPU-Monte Carlo package-gDPM was extended and validated for Elekta Unity online plan verification. Its calculation accuracy and efficiency make it suitable for online independent dose verification for MR-LINAC.
Keywords: GPU-Monte Carlo; MR-LINAC; independent dose verification.
© 2021 American Association of Physicists in Medicine.