PFASs intake from fish, eggs and drinking water in Greece in relation to the safety limits for weekly intake proposed in the EFSA scientific opinion of 2020

Chemosphere. 2022 Jan;286(Pt 3):131851. doi: 10.1016/j.chemosphere.2021.131851. Epub 2021 Aug 9.

Abstract

Food consumption has been recognized as the most significant contributor to human exposure to polyfluoroalkyl and perfluoroalkyl substances (PFASs) for the general population. In 2020, EFSA introduced for the first time safety limit of 4.4 ng/kg body weight (bw) for weekly intake for the sum of perfluorooctanoic acid (PFOA), perfluorooctane sulfonic acid (PFOS), perfluorononanoic acid (PFNA) and perfluorohexane sulfonic acid (PFHxS) which are all perfluoralkyl acids (PFAAs) that belong to PFASs group. Fish and eggs have been found to contribute significantly, almost 50 % to PFOS and PFOA dietary intake of the Greek population. In the present study, estimation of human intake of these four PFASs from fish, eggs and drinking water consumption is attempted. Data from EFSA food consumption database for fish and eggs are used for assessment. Mean weekly intake estimated is above the tolerable weekly intake (TWI) recently proposed, mainly due to fish consumption. Exceedance of the proposed TWI emphasizes the need for continuous monitoring of levels of PFASs in food in parallel with efforts to lower these levels.

Keywords: Dietary intake; Drinking water; Eggs; Fish; PFASs.

MeSH terms

  • Alkanesulfonic Acids* / analysis
  • Animals
  • Caprylates / analysis
  • Drinking Water*
  • Eggs
  • Fluorocarbons* / analysis
  • Greece
  • Humans
  • Sulfonic Acids

Substances

  • Alkanesulfonic Acids
  • Caprylates
  • Drinking Water
  • Fluorocarbons
  • Sulfonic Acids