Symmetrical drug-related intertriginous and flexural exanthema like eruption associated with COVID-19 vaccination

Clin Exp Dermatol. 2022 Jan;47(1):175-176. doi: 10.1111/ced.14898. Epub 2021 Aug 31.


This is a case of symmetrical drug-related intertriginous and flexural exanthema-like eruption following ChAdOx1 nCoV-19 (AstraZeneca-Oxford) vaccination. Investigations, including repeated skin swabs, ruled out an infectious cause. He was subsequently treated with oral prednisolone, which led to a resolution of his symptoms.

Publication types

  • Letter

MeSH terms

  • COVID-19 / prevention & control*
  • ChAdOx1 nCoV-19 / adverse effects*
  • Drug Eruptions / etiology*
  • Exanthema / chemically induced*
  • Humans
  • Intertrigo / chemically induced*
  • Male
  • Middle Aged
  • SARS-CoV-2
  • Vaccination / adverse effects


  • ChAdOx1 nCoV-19