Cardiac Imaging of Acute Myocarditis Following COVID-19 mRNA Vaccination

J Korean Med Sci. 2021 Aug 16;36(32):e229. doi: 10.3346/jkms.2021.36.e229.


Increasing rates of coronavirus disease 2019 (COVID-19) vaccination coverage will result in more vaccine-related side effects, including acute myocarditis. In Korea, we present a 24-year-old male with acute myocarditis following COVID-19 vaccination (BNT162b2). His chest pain developed the day after vaccination and cardiac biomarkers were elevated. Echocardiography showed minimal pericardial effusion but normal myocardial contractility. Electrocardiography revealed diffuse ST elevation in lead II, and V2-5. Cardiac magnetic resonance images showed the high signal intensity of T2- short tau inversion recovery image, the high value of T2 mapping sequence, and late gadolinium enhancement in basal inferior and inferolateral wall. It was presumed that COVID-19 mRNA vaccination was probably responsible for acute myocarditis. Clinical course of the patient was favorable and he was discharged without any adverse event.

Keywords: COVID-19; Myocarditis; Vaccination.

Publication types

  • Case Reports

MeSH terms

  • BNT162 Vaccine
  • COVID-19 / immunology
  • COVID-19 / prevention & control
  • COVID-19 Vaccines / adverse effects*
  • Chest Pain / pathology
  • Echocardiography
  • Electrocardiography
  • Heart / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging
  • Male
  • Myocarditis / diagnostic imaging*
  • Myocarditis / pathology*
  • Myocardium / pathology*
  • Republic of Korea
  • Vaccination / adverse effects
  • Young Adult


  • COVID-19 Vaccines
  • BNT162 Vaccine