Igniting the firestorm: The inflammasome in autoinflammatory syndromes

J Allergy Clin Immunol. 2021 Dec;148(6):1470-1472. doi: 10.1016/j.jaci.2021.07.038. Epub 2021 Aug 14.

Authors

Fiachra Humphries¹, Katherine A Fitzgerald²

Affiliations

¹ Program in Innate Immunity, Department of Medicine, University of Massachusetts Medical School, Worcester, Mass.
² Program in Innate Immunity, Department of Medicine, University of Massachusetts Medical School, Worcester, Mass. Electronic address: kate.fitzgerald@umassmed.edu.

PMID: 34403657
DOI: 10.1016/j.jaci.2021.07.038

No abstract available

Keywords: Inflammasome; autoinflammatory; pyroptosis.

Publication types

Editorial

MeSH terms

Animals
Autoimmune Diseases / immunology*
Humans
Inflammasomes / immunology*
Interleukin-18 / metabolism
Interleukin-1beta / metabolism*
Mutation / genetics
NLR Family, Pyrin Domain-Containing 3 Protein / genetics
Neutrophils / immunology*
Pyroptosis

Substances

Inflammasomes
Interleukin-18
Interleukin-1beta
NLR Family, Pyrin Domain-Containing 3 Protein