Approach to management of pancreatic strictures: the gastroenterologist's perspective

Clin J Gastroenterol. 2021 Dec;14(6):1587-1597. doi: 10.1007/s12328-021-01503-6. Epub 2021 Aug 17.

Abstract

Pancreatic strictures represent a complex clinical problem which often requires multidisciplinary management with a team of gastroenterologists, surgeons and radiologists. Dominant strictures are largely due to inflammatory processes of the pancreas like chronic pancreatitis. However, differentiating benign from malignant processes of the pancreas, leading to strictures is imperative and remains a challenge. With advances in endoscopic management, options for therapy include endoscopic retrograde cholangiopancreatography (ERCP), and endoscopic ultrasound-guided pancreatic drainage (EUS-PD) in situations where ERCP is not feasible or fails. However, endoscopic therapy is suited for a select group of patients and surgery remains key to management in many patients. In this narrative review, we look at the gastroenterologist's perspective and approach to pancreatic ductal strictures, including endoscopic and surgical management.

Keywords: Chronic pancreatitis; ERCP; EUS; Stricture.

Publication types

  • Review

MeSH terms

  • Cholangiopancreatography, Endoscopic Retrograde
  • Constriction, Pathologic / surgery
  • Endosonography
  • Gastroenterologists*
  • Humans
  • Pancreas / diagnostic imaging
  • Pancreatitis, Chronic* / complications
  • Pancreatitis, Chronic* / diagnosis
  • Pancreatitis, Chronic* / therapy