Letter to the Editor: Selpercatinib-Enhanced Radioiodine Uptake in RET-Rearranged Thyroid Cancer

Thyroid. 2021 Oct;31(10):1603-1604. doi: 10.1089/thy.2021.0144. Epub 2021 Sep 17.

Authors

Lionel Groussin¹, Laura Bessiene¹, Jennifer Arrondeau², Simon Garinet³, Béatrix Cochand-Priollet⁴, Audrey Lupo⁴, Jérémie Zerbit⁵, Jérôme Clerc⁶, Olivier Huillard²

Affiliations

¹ Department of Endocrinology, Hopital Cochin, Assistance Publique-Hopitaux de Paris, Université de Paris, Paris, France.
² Department of Medical Oncology, Hopital Cochin, Assistance Publique-Hopitaux de Paris, Université de Paris, Paris, France.
³ Department of Biochemistry, Unit of Pharmacogenetics and Molecular Oncology, Georges Pompidou European Hospital, Assistance Publique-Hopitaux de Paris, Université de Paris, Paris, France.
⁴ Department of Pathology and Hopital Cochin, Assistance Publique-Hopitaux de Paris, Université de Paris, Paris, France.
⁵ Department of Pharmacy, Hopital Cochin, Assistance Publique-Hopitaux de Paris, Université de Paris, Paris, France.
⁶ Department of Nuclear Medicine, Hopital Cochin DMU Imagina, Assistance Publique-Hopitaux de Paris, Université de Paris, Paris, France.

PMID: 34405703
DOI: 10.1089/thy.2021.0144

No abstract available

Publication types

Case Reports
Letter

MeSH terms

Aged
Drug Synergism
Female
Gene Rearrangement / genetics*
Humans
Iodine Radioisotopes / metabolism
Iodine Radioisotopes / therapeutic use*
Lymph Node Excision
Neoplasm Recurrence, Local / genetics*
Neoplasm Recurrence, Local / therapy*
Nuclear Receptor Coactivators / genetics
Oncogene Proteins, Fusion / genetics
Proto-Oncogene Proteins c-ret / genetics*
Pyrazoles / pharmacology*
Pyrazoles / therapeutic use*
Pyridines / pharmacology*
Pyridines / therapeutic use*
Radiopharmaceuticals / metabolism
Radiopharmaceuticals / therapeutic use*
Thyroid Cancer, Papillary / genetics*
Thyroid Cancer, Papillary / metabolism
Thyroid Cancer, Papillary / therapy*
Thyroid Neoplasms / genetics*
Thyroid Neoplasms / metabolism
Thyroid Neoplasms / therapy*
Thyroidectomy

Substances

Iodine Radioisotopes
NCOA4 protein, human
Nuclear Receptor Coactivators
Oncogene Proteins, Fusion
Pyrazoles
Pyridines
Radiopharmaceuticals
selpercatinib
Proto-Oncogene Proteins c-ret
RET protein, human