Cryptogenic organising pneumonia: current understanding of an enigmatic lung disease

Eur Respir Rev. 2021 Aug 17;30(161):210094. doi: 10.1183/16000617.0094-2021. Print 2021 Sep 30.

Abstract

Organising pneumonia (OP) is currently recognised as a nonspecific lung injury response that is associated with a variety of imaging patterns obtained with high-resolution computed tomography (HRCT) of the chest and is characterised histopathologically by the presence of inflammatory cells and a connective tissue matrix within distal airspaces of the lungs. OP is associated with many conditions that include connective tissue disorders, various infections, drug reactions, hypersensitivity pneumonitis and aspiration. When OP cannot be linked to an associated condition and appears to be idiopathic, it is termed cryptogenic organising pneumonia.

Publication types

  • Review

MeSH terms

  • Cryptogenic Organizing Pneumonia* / diagnostic imaging
  • Humans
  • Lung / diagnostic imaging
  • Pneumonia*
  • Tomography, X-Ray Computed