We conducted a matched case-control study to assess the effectiveness of Lyme vaccine (LYMErix) as it was used in clinical practice. We found ≥3 doses to be 71% effective against Lyme disease. This is the first study to show that the Lyme vaccine is effective in a real-world setting.
Keywords: LYMErix; Lyme vaccine; postlicensure; vaccine effectiveness.
© The Author(s) 2021. Published by Oxford University Press on behalf of Infectious Diseases Society of America.