Comparison of Cranioplasty Techniques Following Translabyrinthine Surgery: Implications for Postoperative Pain and Opioid Usage

Otol Neurotol. 2021 Dec 1;42(10):e1565-e1571. doi: 10.1097/MAO.0000000000003295.

Abstract

Objective: To assess differences in postoperative pain, opioid usage, and surgical outcomes between cranioplasty using abdominal fat graft (AFG) versus hydroxyapatite cement (HAC) following translabyrinthine surgery.

Study design: Retrospective case control.

Setting: Tertiary referral center.

Patients: Sixty translabyrinthine procedures were evaluated, including 30 consecutive HAC patients and 30 matched AFG patients. Patients were matched by age, gender, body mass index, and tumor size.

Intervention: Cranioplasty using HAC or AFG following translabyrinthine resection of vestibular schwannoma.

Main outcome measures: Postoperative patient pain ratings, narcotic usage, inpatient length of stay, and complication rates.

Results: Patients who underwent HAC cranioplasty had lower postoperative pain scores on several measures (p < 0.05) and less postoperative narcotic usage (mean difference of 36.7 morphine equivalents, p = 0.0025) when compared to those that underwent AFG closure. HAC cranioplasty patients had shorter average length of hospital stay (2.2 vs 3.4 days, p = 0.0441). Postoperative cerebrospinal fluid leaks (one in HAC group, two in AFG group) and skin reactions in AFG closure patients (n = 1) were infrequent.

Conclusion: HAC cranioplasty is a safe technique comparable to AFG closure following translabyrinthine surgery which can decrease postoperative pain, narcotic usage, and hospital length of stay.

MeSH terms

  • Analgesics, Opioid* / therapeutic use
  • Craniotomy* / adverse effects
  • Craniotomy* / methods
  • Humans
  • Pain, Postoperative / drug therapy
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Skull

Substances

  • Analgesics, Opioid