The trend in application of omics in type 2 diabetes researches; A bibliometric study

Diabetes Metab Syndr. 2021 Sep-Oct;15(5):102250. doi: 10.1016/j.dsx.2021.102250. Epub 2021 Aug 17.

Abstract

Aims: Due to the importance of omics approaches in diabetes diagnosis, we were assumed to study the scientific activities on omics and type 2 diabetes worldwide.

Method: Bibliometric approach was utilized to evaluate the documents on proteomics, lipidomics, and metabolomics in patients with type 2 diabetes in the Scopus database from the beginning to 2020. The articles were screened by two reviewers and the number of publications and citations on omics and type 2 diabetes, top-ranked journals, top-cited articles, country co-contributions, co-authorships, author keywords, and terms were analyzed.

Results: The scientific publications in this field consisted of 551 original articles, of which the USA shares the most percent, followed by China and Germany. The frequent keywords showed that the following hotspots were of interest: "Metabolomics, proteomics, and lipidomics as biomarkers for diabetes", "Omics and diabetic nephropathy", "The application of omics in obesity, insulin resistance, and type 2 diabetes".

Conclusion: This study showed an increasing trend in applying omics in type 2 diabetes researches and determined the leading producers in this field. Besides, the research hotspots and the main subjects of documents were provided for future research and policy decision-making.

Keywords: Bibliometric; Diabetes; Lipidomics; Metabolomics; Omics; Proteomics.

MeSH terms

  • Bibliometrics*
  • Biomarkers / analysis
  • Biomarkers / metabolism*
  • Diabetes Mellitus, Type 2 / diagnosis*
  • Diabetes Mellitus, Type 2 / metabolism
  • Humans
  • Lipidomics / statistics & numerical data*
  • Metabolome*
  • Prognosis
  • Proteome / analysis
  • Proteome / metabolism*

Substances

  • Biomarkers
  • Proteome